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Elevated Cerebral Spinal Fluid Cytokine Levels in Boys with Cerebral Adrenoleukodystrophy Correlates with MRI Severity

BACKGROUND: X-linked adrenoleukodystrophy (ALD) is a metabolic, peroxisomal disease that results from a mutation in the ABCD1 gene. The most severe course of ALD progression is the cerebral inflammatory and demyelinating form of the disease, cALD. To date there is very little information on the cyto...

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Autori principali: Lund, Troy C., Stadem, Paul S., Panoskaltsis-Mortari, Angela, Raymond, Gerald, Miller, Weston P., Tolar, Jakub, Orchard, Paul J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281135/
https://ncbi.nlm.nih.gov/pubmed/22359672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032218
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