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The Two Different Isoforms of the RSC Chromatin Remodeling Complex Play Distinct Roles in DNA Damage Responses

The RSC chromatin remodeling complex has been implicated in contributing to DNA double-strand break (DSB) repair in a number of studies. Both survival and levels of H2A phosphorylation in response to damage are reduced in the absence of RSC. Importantly, there is evidence for two isoforms of this co...

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Autors principals: Chambers, Anna L., Brownlee, Peter M., Durley, Samuel C., Beacham, Tracey, Kent, Nicholas A., Downs, Jessica A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281108/
https://ncbi.nlm.nih.gov/pubmed/22359657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032016
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