Protein Kinase C Iota Regulates Pancreatic Acinar-to-Ductal Metaplasia

Pancreatic acinar-to-ductal metaplasia (ADM) is associated with an increased risk of pancreatic cancer and is considered a precursor of pancreatic ductal adenocarcinoma. Transgenic expression of transforming growth factor alpha (TGF-α) or K-ras(G12D) in mouse pancreatic epithelium induces ADM in viv...

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Autori principali: Scotti, Michele L., Smith, Kristin E., Butler, Amanda M., Calcagno, Shelly R., Crawford, Howard C., Leitges, Michael, Fields, Alan P., Murray, Nicole R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281025/
https://ncbi.nlm.nih.gov/pubmed/22359542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030509
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