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Adaptive Models for Gene Networks
Biological systems are often treated as time-invariant by computational models that use fixed parameter values. In this study, we demonstrate that the behavior of the p53-MDM2 gene network in individual cells can be tracked using adaptive filtering algorithms and the resulting time-variant models ca...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3280989/ https://ncbi.nlm.nih.gov/pubmed/22359614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031657 |
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