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BH3 domains define selective inhibitory interactions with BHRF-1 and KSHV BCL-2

The Epstein–Barr and Kaposi’s sarcoma γ-herpesviruses (KSHVs) are associated with certain cancers, and encode B-cell leukemia/lymphoma 2 (BCL-2) homologs, BHRF-1 and KSHV BCL-2, respectively. Little is known, however, about the molecular interactions allowing viral BCL-2 homologs to mediate their an...

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Detalhes bibliográficos
Main Authors: Flanagan, AM, Letai, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280951/
https://ncbi.nlm.nih.gov/pubmed/18084238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.cdd.4402292
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