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Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5

Toll-like receptors (TLRs) engage networks of transcriptional regulators to induce genes essential for antimicrobial immunity. We report that NFAT5, previously characterized as an osmostress responsive factor, regulates the expression of multiple TLR-induced genes in macrophages independently of osm...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Buxadé, Maria, Lunazzi, Giulia, Minguillón, Jordi, Iborra, Salvador, Berga-Bolaños, Rosa, del Val, Margarita, Aramburu, José, López-Rodríguez, Cristina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280876/
https://ncbi.nlm.nih.gov/pubmed/22312110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111569
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