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Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5
Toll-like receptors (TLRs) engage networks of transcriptional regulators to induce genes essential for antimicrobial immunity. We report that NFAT5, previously characterized as an osmostress responsive factor, regulates the expression of multiple TLR-induced genes in macrophages independently of osm...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3280876/ https://ncbi.nlm.nih.gov/pubmed/22312110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111569 |
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