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Glycine Transporter Inhibitor Attenuates the Psychotomimetic Effects of Ketamine in Healthy Males: Preliminary Evidence

Enhancing glutamate function by stimulating the glycine site of the NMDA receptor with glycine, -serine, or with drugs that inhibit glycine reuptake may have therapeutic potential in schizophrenia. The effects of a single oral dose of cis-N-methyl-N-(6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2...

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Detalhes bibliográficos
Main Authors: D'Souza, Deepak Cyril, Singh, Nagendra, Elander, Jacqueline, Carbuto, Michelle, Pittman, Brian, de Haes, Joanna Udo, Sjogren, Magnus, Peeters, Pierre, Ranganathan, Mohini, Schipper, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280648/
https://ncbi.nlm.nih.gov/pubmed/22113087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.295
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