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The tudor domain protein Kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila

In Drosophila ovaries, distinct Piwi-interacting RNA (piRNA) pathways defend against transposons in somatic and germline cells. Germline piRNAs predominantly arise from bidirectional clusters and are amplified by the ping-pong cycle. In this study, we characterize a novel Drosophila gene, kumo and s...

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Autores principales: Anand, Amit, Kai, Toshie
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280549/
https://ncbi.nlm.nih.gov/pubmed/22157814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.449
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