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The tudor domain protein Kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila
In Drosophila ovaries, distinct Piwi-interacting RNA (piRNA) pathways defend against transposons in somatic and germline cells. Germline piRNAs predominantly arise from bidirectional clusters and are amplified by the ping-pong cycle. In this study, we characterize a novel Drosophila gene, kumo and s...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3280549/ https://ncbi.nlm.nih.gov/pubmed/22157814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.449 |
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