Generation of Polyclonal CMV-specific T Cells for the Adoptive Immunotherapy of Glioblastoma

Glioblastoma (GBM) is the most common primary brain cancer in adults and is virtually incurable. Recent studies have shown that CMV is present in the majority of GBMs. To evaluate if the CMV antigens pp65 and IE1, which are expressed in GBMs, can be targeted with CMV-specific T cells, we measured th...

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Autors principals: Ghazi, Alexia, Ashoori, Aidin, Hanley, Patrick, Salsman, Vita S, Shaffer, Donald R, Kew, Yvonne, Powell, Suzanne Z, Grossman, Robert, Grada, Zakaria, Scheurer, Michael E, Hegde, Meenakshi, Leen, Ann M, Bollard, Catherine M, Rooney, Cliona M, Heslop, Helen E, Gottschalk, Stephen, Ahmed, Nabil
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280423/
https://ncbi.nlm.nih.gov/pubmed/22306904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e318247642f
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