TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy

Targeted T cells are emerging as effective non-toxic therapies for cancer. Multiple elements, however, contribute to the overall pathogenesis of cancer through both distinct and redundant mechanisms. Hence, targeting multiple cancer-specific markers simultaneously could result in better therapeutic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zakaria Grada, Meenakshi Hegde, Tiara Byrd, Donald R Shaffer, Alexia Ghazi, Vita S Brawley, Amanda Corder, Kurt Schönfeld, Joachim Koch, Gianpietro Dotti, Helen E Heslop, Stephen Gottschalk, Winfried S Wels, Matthew L Baker, Nabil Ahmed
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2013-01-01
Cyfres:Molecular Therapy: Nucleic Acids
Pynciau:
bispecific chimeric antigen receptor
CAR
cancer immunotherapy
molecular modeling
T-cell therapy
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2162253116301640
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