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Two high throughput screening assays for Aberrant RNA-protein interactions in Myotonic Dystrophy Type-1
Myotonic dystrophy type-1 (DM1), the most prevalent form of adult muscular dystrophy, is caused by expansion of a CTG repeat in the 3′ untranslated region of the DM protein kinase (DMPK) gene. The pathogenic effects of the CTG expansion arise from the deleterious effects of the mutant transcript. RN...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3280409/ https://ncbi.nlm.nih.gov/pubmed/22218462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-011-5604-0 |
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