Nanobiopolymer for Direct Targeting and Inhibition of EGFR Expression in Triple Negative Breast Cancer

Treatment options for triple negative breast cancer (TNBC) are generally limited to cytotoxic chemotherapy. Recently, anti-epidermal growth factor receptor (EGFR) therapy has been introduced for TNBC patients. We engineered a novel nanobioconjugate based on a poly(β-L-malic acid) (PMLA) nanoplatform...

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Autors principals: Inoue, Satoshi, Patil, Rameshwar, Portilla-Arias, Jose, Ding, Hui, Konda, Bindu, Espinoza, Andres, Mongayt, Dmitriy, Markman, Janet L., Elramsisy, Adam, Phillips, H. Westley, Black, Keith L., Holler, Eggehard, Ljubimova, Julia Y.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280290/
https://ncbi.nlm.nih.gov/pubmed/22355336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031070
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