RhoA/ROCK-dependent moesin phosphorylation regulates AGE-induced endothelial cellular response

BACKGROUND: The role of advanced glycation end products (AGEs) in the development of diabetes, especially diabetic complications, has been emphasized in many reports. Accumulation of AGEs in the vasculature triggers a series of morphological and functional changes in endothelial cells (ECs) and indu...

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Bibliographic Details
Main Authors: Wang, Jiping, Liu, Hongxia, Chen, Bo, Li, Qiang, Huang, Xuliang, Wang, Liqun, Guo, Xiaohua, Huang, Qiaobing
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280169/
https://ncbi.nlm.nih.gov/pubmed/22251897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-11-7
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