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Site specific enzymatic cleavage of RNA.

The hybridization of a DNA oligonucleotide a specific tetramer or longer) will direct a cleavage by RNase H (EC 3.1.4.34) to a specific site in RNA. The resulting fragments can then be labeled at their 5' or 3' ends, purified, and sequenced directly. This procedure is demonstrated with two...

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Hlavní autor: Donis-Keller, H
Médium: Artigo
Jazyk:Inglês
Vydáno: 1979
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC328004/
https://ncbi.nlm.nih.gov/pubmed/386279
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