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Valproic Acid Attenuates Proteinuria and Kidney Injury

Inhibitors of histone deacetylase (HDAC) have anti-inflammatory and antifibrotic effects in several organs and tissues, but their effect on the progression of renal disease is unknown. Here, we studied the effect of valproic acid in adriamycin-induced nephropathy in mice. Administration of valproic...

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Detalhes bibliográficos
Main Authors: Van Beneden, Katrien, Geers, Caroline, Pauwels, Marina, Mannaerts, Inge, Verbeelen, Dierik, van Grunsven, Leo A., Van den Branden, Christiane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279948/
https://ncbi.nlm.nih.gov/pubmed/21868496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010111196
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