Resveratrol supplementation abrogates pro-arteriogenic effects of intramyocardial vascular endothelial growth factor in a hypercholesterolemic swine model of chronic ischemia

BACKGROUND: Clinical trials of therapeutic angiogenesis with vascular endothelial growth factor (VEGF) have been disappointing, owing likely to endothelial dysfunction. We used a swine model of chronic ischemia and endothelial dysfunction to determine whether resveratrol coadministration would impro...

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Autores principales: Chu, Louis M., Robich, Michael P., Lassaletta, Antonio D., Feng, Jun, Laham, Roger J., Burgess, Thomas, Clements, Richard T., Sellke, Frank W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279731/
https://ncbi.nlm.nih.gov/pubmed/21783219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2011.06.009
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