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Improved Detection of the KIT D816V Mutation in Patients with Systemic Mastocytosis Using a Quantitative and Highly Sensitive Real-Time qPCR Assay

The vast majority of patients with systemic mastocytosis (SM) carry the somatic D816V mutation in the KIT gene. The KIT D816V mutation is one of the minor criteria for a diagnosis of SM according to the 2008 World Health Organization classification of myeloproliferative neoplasms. In the present stu...

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Detalhes bibliográficos
Main Authors: Kristensen, Thomas, Vestergaard, Hanne, Møller, Michael Boe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279709/
https://ncbi.nlm.nih.gov/pubmed/21354053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2010.10.004
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