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Inhibition of M. tuberculosis induced signaling by transforming growth factor-β in human mononuclear phagocytes

Tuberculosis (TB) is associated with excessive production and bio-activation of transforming growth factor bets (TGF-β) in situ. Here, modification of expression of components of plasminogen/plasmin pathway in human monocytes (MN) by inhibitors of TGF-β signaling were examined. Smad3 siRNA effective...

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Bibliografiske detaljer
Main Authors: Wu, Mianda, Aung, Htin, Hirsch, Christina S, Toossi, Zahra
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279592/
https://ncbi.nlm.nih.gov/pubmed/22150316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-3083.2011.02668.x
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