Induction of Serine Protease Inhibitor 9 by Mycobacterium tuberculosis Inhibits Apoptosis and Promotes Survival of Infected Macrophages

Our recent microarray analysis of infected human alveolar macrophages (AMs) found serine protease inhibitor 9 (PI-9) to be the most prominently expressed of a cluster of apoptosis-associated genes induced by virulent Mycobacterium tuberculosis. In the current study, we show that induction of PI-9 oc...

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Autores principales: Toossi, Zahra, Wu, Mianda, Rojas, Roxana, Kalsdorf, Barbara, Aung, Htin, Hirsch, Christina S., Walrath, Jessica, Wolbink, Angela, van Ham, Marieke, Silver, Richard F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
Materias:
Major Articles and Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242743/
https://ncbi.nlm.nih.gov/pubmed/22090449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir697
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