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Central Nervous System Delivery of the Antipsychotic Olanzapine Induces Hepatic Insulin Resistance

OBJECTIVE: Olanzapine (OLZ) is an atypical antipsychotic whose clinical efficacy is hampered by side effects including weight gain and diabetes. Recent evidence shows that OLZ alters insulin sensitivity independent of changes in body weight and composition. The present study addresses whether OLZ-in...

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Detalhes bibliográficos
Main Authors: Martins, Paulo J.F., Haas, Michael, Obici, Silvana
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279549/
https://ncbi.nlm.nih.gov/pubmed/20682682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0449
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