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Intramolecular Disulfide Bond between Catalytic Cysteines in an Intein Precursor

Protein splicing is a self-catalyzed and spontaneous post-translational process in which inteins excise themselves out of precursor proteins while the exteins are ligated together. We report the first discovery of an intramolecular disulfide bond between the two active site cysteines, Cys1 and Cys+1...

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Autors principals: Chen, Wen, Li, Lingyun, Du, Zhenming, Liu, Jiajing, Reitter, Julie N., Mills, Kenneth V., Linhardt, Robert J., Wang, Chunyu
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279520/
https://ncbi.nlm.nih.gov/pubmed/22280304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja211010g
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