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An internal disulfide bond acts as a switch for intein activity

Inteins are intervening polypeptides that catalyze their own removal from flanking exteins, concomitant to the ligation of the exteins. The intein that interrupts the DP2 (large) subunit of DNA Polymerase II from Methanoculleus marisnigri (Mma) can promote protein splicing. However, protein splicing...

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Hlavní autoři: Nicastri, Michael C., Xega, Kristina, Li, Lingyun, Xie, Jian, Wang, Chunyu, Linhardt, Robert J., Reitter, Julie N., Mills, Kenneth V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801215/
https://ncbi.nlm.nih.gov/pubmed/23906287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400736c
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