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The mechanisms of microtubule catastrophe and rescue: implications from analysis of a dimer-scale computational model

Microtubule (MT) dynamic instability is fundamental to many cell functions, but its mechanism remains poorly understood, in part because it is difficult to gain information about the dimer-scale events at the MT tip. To address this issue, we used a dimer-scale computational model of MT assembly tha...

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Hlavní autoři: Margolin, Gennady, Gregoretti, Ivan V., Cickovski, Trevor M., Li, Chunlei, Shi, Wei, Alber, Mark S., Goodson, Holly V.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279392/
https://ncbi.nlm.nih.gov/pubmed/22190741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-08-0688
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