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Structural microtubule cap: stability, catastrophe, rescue, and third state.

Microtubules polymerize from GTP-liganded tubulin dimers, but are essentially made of GDP-liganded tubulin. We investigate the tug-of-war resulting from the fact that GDP-liganded tubulin favors a curved configuration, but is forced to remain in a straight one when part of a microtubule. We point ou...

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Bibliografiske detaljer
Main Authors: Jánosi, Imre M, Chrétien, Denis, Flyvbjerg, Henrik
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302230/
https://ncbi.nlm.nih.gov/pubmed/12202357
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