Stress-Induced Cell-Cycle Activation in Tip60 Haploinsufficient Adult Cardiomyocytes

BACKGROUND: Tat-interactive protein 60 (Tip60) is a member of the MYST family of histone acetyltransferases. Studies using cultured cells have shown that Tip60 has various functions including DNA repair, apoptosis and cell-cycle regulation. We globally ablated the Tip60 gene (Htatip), observing that...

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Main Authors: Fisher, Joseph B., Kim, Min-Su, Blinka, Steven, Ge, Zhi-Dong, Wan, Tina, Duris, Christine, Christian, Desirae, Twaroski, Kirk, North, Paula, Auchampach, John, Lough, John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279378/
https://ncbi.nlm.nih.gov/pubmed/22348108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031569
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