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Inactivation of Msx1 and Msx2 in neural crest reveals an unexpected role in suppressing heterotopic bone formation in the head

In an effort to understand the morphogenetic forces that shape the bones of the skull, we inactivated Msx1 and Msx2 conditionally in neural crest. We show that Wnt1-Cre inactivation of up to three Msx1/2 alleles results in a progressively larger defect in the neural crest-derived frontal bone. Unexp...

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Autors principals: Roybal, Paul G., Wu, Nancy L., Sun, Jingjing, Ting, Man-chun, Schaefer, Christopher, Maxson, Robert E.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279331/
https://ncbi.nlm.nih.gov/pubmed/20398647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.04.007
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