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Effects of ethidium bromide on the production of ribosomal RNA in cultured mouse cells.

A treatment of primary mouse kidney cell cultures with 5 microM Ethidium Bromide (Eth Br) reduces the transcription of nuclear-coded genes and especially of ribosomal RNA genes. This effect was consistently observed when comparing drug-treated and control cells for (i), the incorporation of 3H uridi...

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Bibliographic Details
Main Authors: Lange, M, May, P
Format: Artigo
Language:Inglês
Published: 1979
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC327899/
https://ncbi.nlm.nih.gov/pubmed/88722
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