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Effect of 5-alkyl substitution of uracil on the thermal stability of poly [d(A-r5U)] copolymers.

The thermal transition of poly[d(A-r5U)] polydeoxynucleotides (where r was a hydrogen atom, or a methyl, ethyl, n-propyl, n-butyl or n-pentyl group) was studied by measuring the derivative melting profiles of the polymers in the range of 0.01--0.36 M K+, at pH 6.8. According to the Tm values, polyde...

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Main Authors: Sági, J, Brahms, S, Brahms, J, Otvös, L
Formato: Artigo
Idioma:Inglês
Publicado: 1979
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC327897/
https://ncbi.nlm.nih.gov/pubmed/461207
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