ErbB2 Is Necessary for ErbB4 Ligands to Stimulate Oncogenic Activities in Models of Human Breast Cancer

ErbB4 is a member of the ErbB family of receptor tyrosine kinases. This family includes ErbB2 (HER2/Neu), a validated therapeutic target in breast cancer. Several studies indicate that ErbB4 functions as a tumor suppressor in breast cancer, whereas others indicate that ErbB4 functions as an oncogene...

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Bibliografiske detaljer
Main Authors: Mill, Christopher P., Zordan, Michael D., Rothenberg, S. Michael, Settleman, Jeffrey, Leary, James F., Riese, David J.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2011
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278901/
https://ncbi.nlm.nih.gov/pubmed/22393464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911431080
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