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A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fasting

To find new genes that influence liver lipid mass, we performed a genetic screen for zebrafish mutants with hepatic steatosis, a pathological accumulation of fat. The red moon (rmn) mutant develops hepatic steatosis as maternally deposited yolk is depleted. Conversely, hepatic steatosis is suppresse...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hugo, Sarah E., Cruz-Garcia, Lourdes, Karanth, Santhosh, Anderson, Ryan M., Stainier, Didier Y.R., Schlegel, Amnon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278895/
https://ncbi.nlm.nih.gov/pubmed/22302940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.180968.111
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