MIRA-SNuPE, a quantitative, multiplex method for measuring allele-specific DNA methylation

5-methyl-C (5mC) and 5-hydroxymethyl-C (5hmC) are epigenetic marks with well-known and putative roles in gene regulation, respectively. These two DNA covalent modifications cannot be distinguished by bisulfite sequencing or restriction digestion, the standard methods of 5mC detection. The methylated...

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Main Authors: Lee, Dong-Hoon, Tran, Diana A, Singh, Purnima, Oates, Nathan, Rivas, Guillermo E, Larson, Garrett P, Pfeifer, Gerd P, Szabó, Piroska E
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2011
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278787/
https://ncbi.nlm.nih.gov/pubmed/20948294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.2.13699
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