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A dp53/JNK-dependant feedback amplification loop is essential for the apoptotic response to stress in Drosophila

Programmed cell death (apoptosis) is a conserved process aimed to eliminate unwanted cells. The key molecules are a group of proteases called caspases that cleave vital proteins, which leads to the death of cells. In Drosophila, the apoptotic pathway is usually represented as a cascade of events in...

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Detalhes bibliográficos
Main Authors: Shlevkov, E, Morata, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278728/
https://ncbi.nlm.nih.gov/pubmed/21886179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.113
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