A Chemical Genetics Approach Reveals H,K-ATPase-Mediated Membrane Voltage is Required for Planarian Head Regeneration

Biophysical signaling is required for both embryonic polarity and regenerative outgrowth. Exploiting endogenous ion transport for regenerative therapies will require direct regulation of membrane voltage. Here, we develop a pharmacological method to target ion transporters, uncovering a novel role f...

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Bibliografiske detaljer
Main Authors: Beane, Wendy Scott, Morokuma, Junji, Adams, Dany Spencer, Levin, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278711/
https://ncbi.nlm.nih.gov/pubmed/21276941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.11.012
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