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Immune complexes and late complement proteins trigger activation of Syk tyrosine kinase in human CD4(+) T cells

In systemic lupus erythematosus (SLE), the autoantibodies that form immune complexes (ICs) trigger activation of the complement system. This results in the formation of membrane attack complex (MAC) on cell membrane and the soluble terminal complement complex (TCC). Hyperactive T cell responses are...

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Detalhes bibliográficos
Main Authors: Chauhan, A K, Moore, T L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278689/
https://ncbi.nlm.nih.gov/pubmed/22235999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04505.x
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