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Application of a Sequential Multicomponent Assembly Process/Huisgen Cycloaddition Strategy to the Preparation of Libraries of 1,2,3-Triazole-Fused 1,4-Benzodiazepines

A strategy featuring a multicomponent assembly process followed by an intramolecular azide–alkyne dipolar (Huisgen) cycloaddition was implemented for the facile synthesis of three different 1,2,3-triazolo-1,4-benzodiazepine scaffolds. A diverse library of 170 compounds derived from these scaffolds w...

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Detalhes bibliográficos
Main Authors: Donald, James R., Wood, Rebekah R., Martin, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278535/
https://ncbi.nlm.nih.gov/pubmed/22273436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co2002087
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