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Evolutionary Origins of Transcription Factor Binding Site Clusters
Empirical studies have revealed that regulatory DNA sequences such as enhancers or promoters often harbor multiple binding sites for the same transcription factor. Such “homotypic site clustering” has been hypothesized as arising out of functional requirements of the sequences. Here, we propose an a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278477/ https://ncbi.nlm.nih.gov/pubmed/22075113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msr277 |
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