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Evolutionary Origins of Transcription Factor Binding Site Clusters

Empirical studies have revealed that regulatory DNA sequences such as enhancers or promoters often harbor multiple binding sites for the same transcription factor. Such “homotypic site clustering” has been hypothesized as arising out of functional requirements of the sequences. Here, we propose an a...

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Bibliografiska uppgifter
Huvudupphovsmän: He, Xin, Duque, Thyago S.P.C., Sinha, Saurabh
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278477/
https://ncbi.nlm.nih.gov/pubmed/22075113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msr277
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