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Inhibition of Post-Synaptic Kv7/KCNQ/M Channels Facilitates Long-Term Potentiation in the Hippocampus

Activation of muscarinic acetylcholine receptors (mAChR) facilitates the induction of synaptic plasticity and enhances cognitive function. In the hippocampus, M(1) mAChR on CA1 pyramidal cells inhibit both small conductance Ca(2+)-activated KCa2 potassium channels and voltage-activated Kv7 potassium...

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Detalhes bibliográficos
Main Authors: Petrovic, Milos M., Nowacki, Jakub, Olivo, Valeria, Tsaneva-Atanasova, Krasimira, Randall, Andrew D., Mellor, Jack R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278412/
https://ncbi.nlm.nih.gov/pubmed/22348007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030402
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