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Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice

BACKGROUND: Peroxisome proliferator activated receptor alpha (PPARα) regulates lipids metabolism and inhibits inflammatory response. However, the role of PPARα in alcoholic liver disease is largely unknown. We aim to elucidate the effect and the molecular basis of PPARα in ethanol induced hepatic in...

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Detalhes bibliográficos
Main Authors: Kong, Lingbo, Ren, Weiguang, Li, Wencong, Zhao, Suxian, Mi, Hongmei, Wang, Rongqi, Zhang, Yuguo, Wu, Wenjuan, Nan, Yuemin, Yu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278384/
https://ncbi.nlm.nih.gov/pubmed/22208561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-10-246
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