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The Lipid Sulfatide Is a Novel Myelin-Associated Inhibitor of CNS Axon Outgrowth

CNS myelin is strongly inhibitory to growing axons and is thought to be a major contributor to CNS axon regenerative failure. Although a number of proteins present in myelin, including Nogo, MAG, and oligodendrocyte-myelin glycoprotein (OMgp), have been identified as myelin-associated inhibitors, st...

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Autores principales: Winzeler, Alissa M., Mandemakers, Wim J., Sun, Matthew Z., Stafford, Melissa, Phillips, Carolyn T., Barres, Ben A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277869/
https://ncbi.nlm.nih.gov/pubmed/21525289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3004-10.2011
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