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Polar Assembly and Scaffolding Proteins of the Virulence-Associated ESX-1 Secretory Apparatus in Mycobacteria

The ESX-1 secretion system is required for pathogenicity of Mycobacterium tuberculosis (Mtb). Despite considerable research, little is known about the structural components of ESX-1, or how these proteins are assembled into the active secretion apparatus. Here, we exploit the functionally related ES...

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Detalhes bibliográficos
Main Authors: Wirth, Samantha E., Krywy, Janet A., Aldridge, Bree, Fortune, Sarah, Fernandez-Suarez, Marta, Gray, Todd A., Derbyshire, Keith M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277861/
https://ncbi.nlm.nih.gov/pubmed/22233444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07958.x
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