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ESX-1 Secreted Virulence Factors Are Recognized by Multiple Cytosolic AAA ATPases in Pathogenic Mycobacteria

The ESX-1 secretion system of M. tuberculosis delivers bacterial virulence factors to host cells during infection. The most abundant factor, the ESAT-6/CFP-10 dimer, is targeted for secretion via a C-terminal signal sequence on CFP-10 that is recognized by the cytosolic ATPase, Rv3871. However, the...

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Bibliografiska uppgifter
Huvudupphovsmän: DiGiuseppe Champion, Patricia A., Champion, Matthew M., Manzanillo, Paolo, Cox, Jeffery S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023814/
https://ncbi.nlm.nih.gov/pubmed/19682254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06821.x
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