Characterization of Inhibitors of Glucocorticoid Receptor Nuclear Translocation: A Model of Cytoplasmic Dynein-Mediated Cargo Transport

Agonist-induced glucocorticoid receptor [GR] transport from the cytoplasm to the nucleus was used as a model to identify dynein-mediated cargo transport inhibitors. Cell-based screening of the library of pharmacologically active compound (LOPAC)-1280 collection identified several small molecules tha...

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Bibliografiske detaljer
Main Authors: Daghestani, Hikmat N., Zhu, Guangyu, Johnston, Paul A., Shinde, Sunita N., Brodsky, Jeffrey L., Day, Billy W.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2012
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277738/
https://ncbi.nlm.nih.gov/pubmed/21919741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2010.0367
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