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Domain-Based Biosensor Assay to Screen for Epidermal Growth Factor Receptor Modulators in Live Cells
Traditional drug discovery efforts have resulted in the approval of a handful of receptor tyrosine kinase (RTK) inhibitors; however, their discovery relied solely on screening recombinant kinases, often with poor cellular activity outcome. The ability to screen RTKs in their natural environment is s...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Mary Ann Liebert, Inc.
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277729/ https://ncbi.nlm.nih.gov/pubmed/22280060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2011.423 |
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