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IL-6 contributes to an immune tolerance checkpoint in post germinal center B cells
The generation of a B cell repertoire involves producing and subsequently purging autoreactive B cells. Receptor editing, clonal deletion and anergy are key mechanisms of central B cell tolerance. Somatic mutation of antigen-activated B cells within the germinal center produces a second wave of auto...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277677/ https://ncbi.nlm.nih.gov/pubmed/22154464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2011.09.004 |
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