Correlation of DNA Hypomethylation at Pericentromeric Heterochromatin Regions of Chromosomes 16 and 1 with Histological Features and Chromosomal Abnormalities of Human Breast Carcinomas

Changes in DNA methylation status are not only important for regulating gene expression but are also suggested to induce chromosome instability. To reveal the correlation of DNA methylation status in heterochromatin regions with tumor histology and with chromosome alterations, DNA methylation status...

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Bibliographic Details
Main Authors: Tsuda, Hitoshi, Takarabe, Teruko, Kanai, Yae, Fukutomi, Takashi, Hirohashi, Setsuo
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277345/
https://ncbi.nlm.nih.gov/pubmed/12213714
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