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Differential effects of a polyalanine tract expansion in Arx on neural development and gene expression
Polyalanine (poly-A) tracts exist in 494 annotated proteins; to date, expansions in these tracts have been associated with nine human diseases. The pathogenetic mechanism by which a poly-A tract results in these various human disorders remains uncertain. To understand the role of this mutation type,...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277309/ https://ncbi.nlm.nih.gov/pubmed/22108177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr538 |
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