Treatment of Metastatic Melanoma with Autologous CD4+ T Cells against NY-ESO-1

We developed an in vitro method for isolating and expanding autologous CD4+ T-cell clones with specificity for the melanoma-associated antigen NY-ESO-1. We infused these cells into a patient with refractory metastatic melanoma who had not undergone any previous conditioning or cytokine treatment. We...

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Detalhes bibliográficos
Main Authors: Hunder, Naomi N., Wallen, Herschel, Cao, Jianhong, Hendricks, Deborah W., Reilly, John Z., Rodmyre, Rebecca, Jungbluth, Achim, Gnjatic, Sacha, Thompson, John A., Yee, Cassian
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277288/
https://ncbi.nlm.nih.gov/pubmed/18565862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0800251
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